Search on: ORNITHINE CARBOXY-LYASE 
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Descriptor English:   Ornithine Decarboxylase 
Descriptor Spanish:   Ornitina Descarboxilasa 
Descriptor Portuguese:   Ornitina Descarboxilase 
Synonyms English:   Ornithine Carboxy-lyase  
Tree Number:   D08.811.520.224.125.425
Definition English:   A pyridoxal-phosphate protein, believed to be the rate-limiting compound in the biosynthesis of polyamines. It catalyzes the decarboxylation of ornithine to form putrescine, which is then linked to a propylamine moiety of decarboxylated S-adenosylmethionine to form spermidine. EC 4.1.1.17. 
History Note English:   84(75); was see under CARBOXY-LYASES 1975-83 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   10133 
Unique Identifier:   D009955 

Occurrence in VHL:
 

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